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Progress in studies of sex determination mechanisms and sex control techniques in

Qian ZHOU,Songlin CHEN

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 2,   Pages 113-123 doi: 10.15302/J-FASE-2016093

Abstract: It has a female heterogametic sex determination system (ZW/ZZ) and environmental factors can induce sex-reversalfemales grow much faster than males and it is feasible to improve the aquaculture production through sexThis paper reviews the progress in research on sex determination mechanisms research in our laboratoryand for differentiation of the fish sex.sex management in artificial culturing of .

Keywords： Cynoglossus semilaevis     sex determination     sex control technique    

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Efficacy of intelligent diagnosis with a dynamic uncertain causality graph model for rare disorders of sex

Dongping Ning, Zhan Zhang, Kun Qiu, Lin Lu, Qin Zhang, Yan Zhu, Renzhi Wang

Frontiers of Medicine 2020, Volume 14, Issue 4,   Pages 498-505 doi: 10.1007/s11684-020-0791-8

Abstract: Disorders of sex development (DSD) are a group of rare complex clinical syndromes with multiple etiologies

Keywords： disorders of sex development (DSD)     intelligent diagnosis     dynamic uncertain causality graph    

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Genomic regions associated with the sex-linked inhibitor of dermal melanin in Silkie chicken

Ming TIAN,Rui HAO,Suyun FANG,Yanqiang WANG,Xiaorong GU,Chungang FENG,Xiaoxiang HU,Ning LI

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 3,   Pages 242-249 doi: 10.15302/J-FASE-2014018

Abstract: This dermal hyperpigmentation phenotype is controlled by the sex-linked inhibitor of dermal melanin gene

Keywords： sex-linked inhibitor of dermal melanin (Id)     Silkie     chromosome Z    

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Self-assembly of metal-cholesterol oxidase hybrid nanostructures and application in bioconversion of steroids

Yu Xin, Qiuyue Gao, Yu Gu, Mengyao Hao, Guangming Fan, Liang Zhang

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 3,   Pages 615-629 doi: 10.1007/s11705-020-1989-7

Abstract: A cholesterol oxidase (COD) was hybridized with Ca , Zn , Al , Fe and Mn . After precipitation with PO at 4 °C for 72 h, the resulting pellets were freeze-dried. In scanning electron microscopy assays, the metal-COD complexes revealed flower-like or granular structures after hybridization. Fourier transform infrared spectroscopy assay revealed the characteristic peaks of both the enzyme and metal materials. X-ray diffraction analysis indicated that COD was encapsulated in CaHPO ·2H O-, Zn (PO ) ·4H O-, AlPO -, FeP - and Mn (PO ) ·3H O-based nanostructures, respectively. Differential scanning calorimetry assay indicated significant increases in thermo-denaturation temperatures from 60.5 °C to 167.02 °C, 167.02 °C, 137.70 °C, 172.85 °C and 160.99 °C, respectively. Using steroid derivatives as substrates, this enzyme could convert cholesterol, pregnenolone, dehydroepiandrosterone, ergosterol, -sitosterol and stigmasterol to related single products. Hybridization in metal-based nanostructures could significantly enhance the initial conversion ratio and reaction stability of the enzyme. In addition, substrate selectivity could be affected by various metal materials. Briefly, using Ca , Zn , Al , Fe and Mn as hybrid raw materials could help to encapsulate COD in related metal-enzyme nanostructures, and could help to promote the stability and tolerant properties of the enzyme, while also enhancing its catalytic characteristics.

Keywords： cholesterol oxidase     metal-enzyme hybridization     nanostructures     sterol derivatives     bioconversion    

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Isolation and characterization of a bacterial strain that efficiently degrades sex steroid hormones

JI Shulan, LIU Zhipeng, REN Haiyan, LIU Zhipei

Frontiers of Environmental Science & Engineering 2007, Volume 1, Issue 3,   Pages 325-328 doi: 10.1007/s11783-007-0055-8

Abstract: A bacterial strain, ZY3, growing on sex steroid hormones as the sole source of carbon and energy wasisolated from the sewage treatment plant of a prophylactic steroids factory.The degradation rate of the sex steroid hormones increased to 87% and 85% after the addition of maltose

Keywords： maltose     optimum temperature     prophylactic     3-methoxy-17-hydroxy-1     3     5     addition    

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Successful production of an all-female common carp (Cyprinus carpio L.) population using cyp17a1-deficient neomale carp Article

Gang Zhai,Tingting Shu,Kuangxin Chen,Qiyong Lou,Jingyi Jia,Jianfei Huang,Chuang Shi,Xia Jin,Jiangyan He,Donghuo Jiang,Xueqiao Qian,Wei Hu,Zhan Yin,

Engineering 2022, Volume 8, Issue 1,   Pages 181-189 doi: 10.1016/j.eng.2021.03.026

Abstract: the most widely practiced technique available for the mass production of monosex fish populations is sexsteroid-induced sex reversal.all-male phenotype for homozygous cyp17a1-deficient carp, regardless of the individuals’ sex-determination

Keywords： Common carp     Sexual dimorphism     Growth     cyp17a1     Sex steroids     All-female population    

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Possibility of women treated with fertility-sparing surgery for non-epithelial ovarian tumors to safely and successfully become pregnant---a Chinese retrospective cohort study among 148 cases

Bin Yang, Yan Yu, Jing Chen, Yan Zhang, Ye Yin, Nan Yu, Ge Chen, Shifei Zhu, Haiyan Huang, Yongqun Yuan, Jihui Ai, Xinyu Wang, Kezhen Li

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 509-517 doi: 10.1007/s11684-017-0554-3

Abstract:

This study was performed to evaluate the oncological and reproductive outcomes of childbearing-age women treated with fertility-sparing surgery (FSS) for non-epithelial ovarian tumors in China. One hundred and forty eight non-epithelial ovarian tumor women treated with FSS between January 1, 2000 and August 31, 2015 from two medical centers in China were identified. Progression-free survival (PFS) was 88.5%, whereas overall survival (OS) was 93.9%. Univariate analysis suggested that delivery after treatment is related to PFS (P=0.023), whereas histology significantly influenced OS. Cox regression analysis suggested that only histology was associated with PFS and OS (P<0.05). Among the 129 women who completed adjuvant chemotherapy (ACT), none developed amenorrhea. Among the 44 women who desired pregnancy, 35 (79.5%) successfully had 51 gestations including 35 live births without birth defects. Non-epithelial ovarian tumors can achieve fulfilling prognosis after FSS and chemotherapy. Histology might be the only independent prognostic factor for PFS and OS. FSS followed by ACT appeared to have little or no effect on fertility. Meanwhile, postoperative pregnancy did not increase the PFS or OS. Use of gonadotropin-releasing hormone agonist was not beneficial for fertility.

Keywords： malignant germ cell tumors     ovarian sex cord-stromal tumors     fertility-sparing surgery     prognosis     fertility    

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Periodic Changes in the N-Glycosylation of Immunoglobulin G During the Menstrual Cycle Article

Julija Jurić, Hongli Peng, Manshu Song, Frano Vučković, Jelena Šimunović, Irena Trbojević-Akmačić, Youxin Wang, Jiaonan Liu, Qing Gao, Hao Wang, Qiaoyun Chu, Marija Pezer, Wei Wang, Gordan Lauc

Engineering 2023, Volume 26, Issue 7,   Pages 108-118 doi: 10.1016/j.eng.2022.10.020

Abstract: The modification of IgG N-glycosylation is considered to be one of the various mechanisms by which sexAlthough the menstrual cycle is the central sex hormone-related physiological process in most women ofcyclic periodic changes in the N-glycosylation of IgG in association with the menstrual cycle phase and sex

Keywords： N-glycosylation     Immunoglobulin G     Menstrual cycle     Female sex hormones     Estrogen     Progesterone     Testosterone    

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Title Author Date Type Operation

Progress in studies of sex determination mechanisms and sex control techniques in

Qian ZHOU,Songlin CHEN

Journal Article

Efficacy of intelligent diagnosis with a dynamic uncertain causality graph model for rare disorders of sex

Dongping Ning, Zhan Zhang, Kun Qiu, Lin Lu, Qin Zhang, Yan Zhu, Renzhi Wang

Journal Article

Genomic regions associated with the sex-linked inhibitor of dermal melanin in Silkie chicken

Ming TIAN,Rui HAO,Suyun FANG,Yanqiang WANG,Xiaorong GU,Chungang FENG,Xiaoxiang HU,Ning LI

Journal Article

Self-assembly of metal-cholesterol oxidase hybrid nanostructures and application in bioconversion of steroids

Yu Xin, Qiuyue Gao, Yu Gu, Mengyao Hao, Guangming Fan, Liang Zhang

Journal Article

Isolation and characterization of a bacterial strain that efficiently degrades sex steroid hormones

JI Shulan, LIU Zhipeng, REN Haiyan, LIU Zhipei

Journal Article

Successful production of an all-female common carp (Cyprinus carpio L.) population using cyp17a1-deficient neomale carp

Gang Zhai,Tingting Shu,Kuangxin Chen,Qiyong Lou,Jingyi Jia,Jianfei Huang,Chuang Shi,Xia Jin,Jiangyan He,Donghuo Jiang,Xueqiao Qian,Wei Hu,Zhan Yin,

Journal Article

Possibility of women treated with fertility-sparing surgery for non-epithelial ovarian tumors to safely and successfully become pregnant---a Chinese retrospective cohort study among 148 cases

Bin Yang, Yan Yu, Jing Chen, Yan Zhang, Ye Yin, Nan Yu, Ge Chen, Shifei Zhu, Haiyan Huang, Yongqun Yuan, Jihui Ai, Xinyu Wang, Kezhen Li

Journal Article

Periodic Changes in the N-Glycosylation of Immunoglobulin G During the Menstrual Cycle

Julija Jurić, Hongli Peng, Manshu Song, Frano Vučković, Jelena Šimunović, Irena Trbojević-Akmačić, Youxin Wang, Jiaonan Liu, Qing Gao, Hao Wang, Qiaoyun Chu, Marija Pezer, Wei Wang, Gordan Lauc

Journal Article